Nature of Business and Accounting Policies - Revenue Recognition (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2016	Dec. 31, 2015	Dec. 31, 2014
Activity related to product revenues allowances and reserve categories
Beginning Balance	$ 49,296	$ 36,023	$ 87,133
Provision related to current period sales	163,922	81,205	48,006
Adjustments related to prior period sales	(104)	(20,852)	3,270
Credits/payments made	(123,913)	(47,080)	(102,386)
Ending Balance	89,201	49,296	36,023
Trade Allowances
Activity related to product revenues allowances and reserve categories
Beginning Balance	2,089	1,463	1,535
Provision related to current period sales	20,075	10,890	8,468
Adjustments related to prior period sales	(90)	(214)	(43)
Credits/payments made	(19,506)	(10,050)	(8,497)
Ending Balance	2,568	2,089	1,463
Rebates, Chargebacks and Discounts
Activity related to product revenues allowances and reserve categories
Beginning Balance	44,669	29,102	68,244
Provision related to current period sales	134,198	65,781	35,713
Adjustments related to prior period sales	154	(19,410)	329
Credits/payments made	(97,094)	(30,804)	(75,184)
Ending Balance	81,927	44,669	29,102
Product Returns
Activity related to product revenues allowances and reserve categories
Beginning Balance	1,228	4,713	15,799
Provision related to current period sales	3,047	779	2,478
Adjustments related to prior period sales	(17)	(993)	3,056
Credits/payments made	(766)	(3,271)	(16,620)
Ending Balance	3,492	1,228	4,713
Other Incentives
Activity related to product revenues allowances and reserve categories
Beginning Balance	1,310	745	1,555
Provision related to current period sales	6,602	3,755	1,347
Adjustments related to prior period sales	(151)	(235)	(72)
Credits/payments made	(6,547)	(2,955)	(2,085)
Ending Balance	$ 1,214	$ 1,310	$ 745