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Stock-based Compensation Expense (Tables)
12 Months Ended
Dec. 31, 2016
Disclosure of Compensation Related Costs, Share-based Payments [Abstract]  
Stock-based compensation expense by line item
The effect of stock-based compensation expense during the three years ended December 31, 2016 was as follows:
 
2016
 
2015
 
2014
 
(in thousands)
Stock-based compensation expense by line item:
 
 
 
 
 
Research and development expenses
$
153,451

 
$
152,955

 
$
116,998

Sales, general and administrative expenses
84,254

 
78,070

 
60,544

Total stock-based compensation expense included in costs and expenses
$
237,705

 
$
231,025

 
$
177,542

Stock-based compensation expense by type of award
The stock-based compensation expense by type of award during the three years ended December 31, 2016 was as follows:
 
2016
 
2015
 
2014
 
(in thousands)
Stock-based compensation expense by type of award:
 
 
 
 
 
Stock options
$
114,768

 
$
129,276

 
$
99,961

Restricted stock and restricted stock units
118,709

 
98,811

 
70,678

ESPP share issuances
7,835

 
7,025

 
8,326

Less: stock-based compensation expense capitalized to inventories
(3,607
)
 
(4,087
)
 
(1,423
)
Total stock-based compensation expense included in costs and expenses
$
237,705

 
$
231,025

 
$
177,542

Unrecognized stock-based compensation expense, net of estimated forfeitures
The following table sets forth the Company’s unrecognized stock-based compensation expense, net of estimated forfeitures, as of December 31, 2016, by type of award and the weighted-average period over which that expense is expected to be recognized:
 
As of December 31, 2016
 
Unrecognized Expense
Net of
Estimated Forfeitures
 
Weighted-average
Recognition
Period
 
(in thousands)
 
(in years)
Type of award:
 
 
 
Stock options
$
157,819

 
2.50
Restricted stock and restricted stock units
$
176,972

 
2.39
ESPP share issuances
$
4,080

 
0.58
Schedule of assumptions used to estimate the grant date fair value of options
The fair value of each option granted during 2016, 2015 and 2014 was estimated on the date of grant using the Black-Scholes option pricing model with the following weighted-average assumptions:
 
2016
 
2015
 
2014
Expected stock price volatility
46.77
%
 
47.29
%
 
50.86
%
Risk-free interest rate
1.32
%
 
1.61
%
 
1.77
%
Expected term of options (in years)
4.91

 
5.28

 
5.47

Expected annual dividends

 

 

Schedule of assumptions used to estimate the grant date fair value employee stock purchase plan
The following table reflects the weighted-average assumptions used in the Black-Scholes option pricing model for 2016, 2015 and 2014:
 
2016
 
2015
 
2014
Expected stock price volatility
48.22
%
 
47.20
%
 
60.32
%
Risk-free interest rate
0.56
%
 
0.40
%
 
0.09
%
Expected term (in years)
0.75

 
0.72

 
0.75

Expected annual dividends