Carrying value as of the balance sheet date of liabilities incurred (and for which invoices have typically been received) and payable to vendors for goods and services received that are used in an entity's business. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer).

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Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	instant

- Definition

Carrying value as of the balance sheet date of obligations incurred and payable, pertaining to costs that are statutory in nature, are incurred on contractual obligations, or accumulate over time and for which invoices have not yet been received or will not be rendered. Examples include taxes, interest, rent and utilities. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer).

Collaborative Arrangements - Aggregate VIE Financial Information (Details) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2016	Mar. 31, 2015	Dec. 31, 2015	Jun. 04, 2015
Variable Interest Entity, Primary Beneficiary, Does Not Hold Majority Voting Interest, Disclosures [Abstract]
Provision for (benefit from) income taxes	$ 5,485	$ 299
Net (income) loss attributable to noncontrolling interest	(5,529)	98
Variable Interest Entity, Consolidated, Carrying Amount, Assets and Liabilities, Net:
Restricted cash and cash equivalents (VIE)	76,273		$ 78,910
Prepaid expenses and other current assets	55,866		50,935
Intangible assets	284,340		284,340
Goodwill	50,384		50,384
Other assets	7,600		6,912
Accounts payable	75,221		74,942
Other current liabilities	272,665		305,820
Deferred tax liability, net	112,259		110,439
Other liabilities	31,822		31,778
Noncontrolling interest	159,119		153,661
BioAxone Biosciences Inc
Variable Interest Entity, Primary Beneficiary, Does Not Hold Majority Voting Interest, Disclosures [Abstract]
Increase in fair value of contingent milestone and royalty payments	400	100
Contingent consideration, liability	28,400		28,000
Parion Sciences, Inc
Variable Interest Entity, Primary Beneficiary, Does Not Hold Majority Voting Interest, Disclosures [Abstract]
Provision for (benefit from) income taxes	3,100
Increase in fair value of contingent milestone and royalty payments	9,000
Contingent consideration, liability	188,000		179,000
Variable Interest Entity, Consolidated, Carrying Amount, Assets and Liabilities, Net:
Intangible assets				$ 255,340
Goodwill				10,468
Deferred tax liability, net				$ 91,023
Variable Interest Entity, Primary Beneficiary
Variable Interest Entity, Primary Beneficiary, Does Not Hold Majority Voting Interest, Disclosures [Abstract]
Loss attributable to noncontrolling interest before provision for income taxes	839	287
Provision for (benefit from) income taxes	3,062	(64)
Increase in fair value of contingent milestone and royalty payments	9,430	125
Net (income) loss attributable to noncontrolling interest	(5,529)	$ 98
Variable Interest Entity, Consolidated, Carrying Amount, Assets and Liabilities, Net:
Restricted cash and cash equivalents (VIE)	76,273		78,910
Prepaid expenses and other current assets	2,818		3,138
Intangible assets	284,340		284,340
Goodwill	19,391		19,391
Other assets	434		455
Accounts payable	1,569		676
Taxes payable	24,512		24,554
Other current liabilities	6,595		7,100
Deferred tax liability, net	112,259		110,438
Other liabilities	310		300
Noncontrolling interest	$ 159,119		$ 153,661