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Other Arrangements (Details) - USD ($)
$ in Millions
1 Months Ended 12 Months Ended
Apr. 30, 2014
Dec. 31, 2008
Dec. 31, 2015
Sale of HIV Protease Inhibitor Royalty Stream      
Gross proceeds from sale of royalty rights receivable from GlaxoSmithKline   $ 160.0  
Royalty purchase agreement deferred revenue     $ 26.0
Other nonoperating Income $ 36.7