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Collaborative Arrangements Collaborative Arrangements (Details) - USD ($)
$ in Thousands
3 Months Ended 6 Months Ended 12 Months Ended
Jun. 04, 2015
Jun. 30, 2015
Jun. 30, 2014
Jun. 30, 2015
Jun. 30, 2014
Dec. 31, 2014
Recognized Collaborative Revenue [Abstract]            
Royalty revenues   $ 5,077 $ 13,015 $ 11,869 $ 23,748  
Collaborative revenues   611 3,087 1,453 7,344  
Total revenues attributable to the Janssen NV collaboration   166,076 138,421 304,585 256,872  
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Net [Abstract]            
Intangible assets   284,340   284,340   $ 29,000
Goodwill   50,384   50,384   39,915
Deferred tax liability   (112,413)   (112,413)   (15,044)
Restricted cash and cash equivalents (VIE)   88,318   88,318   8,418
Prepaid expenses and other current assets   53,289   53,289   44,175
Other assets   9,136   9,136   3,265
Accounts payable   72,703   72,703   71,194
Accrued expenses   206,030   206,030   209,676
Other liabilities, excluding current portion   41,252   41,252   21,707
Noncontrolling interest   153,252   153,252   21,177
Loss attributable to noncontrolling interest before provision for income taxes   (190,861) (158,396) (389,266) (389,704)  
Income tax provision   (30,131) (693) (30,430) (1,496)  
Net loss attributable to noncontrolling interest   (32,144) 0 (32,242) 0  
Janssen            
Recognized Collaborative Revenue [Abstract]            
Royalty revenues   59 5,698 1,584 10,633  
Collaborative revenues   537 1,483 1,179 2,872  
Total revenues attributable to the Janssen NV collaboration   596 $ 7,181 2,763 $ 13,505  
Up-front payment           35,000
Parion Sciences, Inc            
Recognized Collaborative Revenue [Abstract]            
Up-front payment $ 80,000          
Fair value of contingent milestone and royalty payments 175,340          
Business combination, consideration transferred 255,340          
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Net [Abstract]            
Intangible assets 255,340          
Goodwill 10,468          
Deferred tax liability (91,023)          
Net other assets (liabilities) (10,468)          
Net assets attributable to noncontrolling interests $ 164,317          
Income tax provision       (29,700)    
Increase (decrease) in fair value of contingent milestone and royalty payments   (1,600)        
Variable Interest Entity, Primary Beneficiary            
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Net [Abstract]            
Intangible assets   284,340   284,340   29,000
Goodwill   19,391   19,391   8,923
Deferred tax liability   (108,913)   (108,913)   (11,544)
Restricted cash and cash equivalents (VIE)   88,318   88,318   8,418
Prepaid expenses and other current assets   895   895   268
Other assets   508   508   42
Accounts payable   823   823   189
Accrued expenses   34,254   34,254   3,891
Other liabilities, excluding current portion   6,068   6,068   300
Noncontrolling interest   153,252   153,252   $ 21,177
Loss attributable to noncontrolling interest before provision for income taxes   (1,293)   (1,579)    
Income tax provision   (29,653)   (29,590)    
Increase (decrease) in fair value of contingent milestone and royalty payments   (1,198)   (1,073)    
Net loss attributable to noncontrolling interest   $ (32,144)   $ (32,242)