Condensed Consolidated Statements of Cash Flows (USD $) In Thousands, unless otherwise specified	6 Months Ended
	Jun. 30, 2014	Jun. 30, 2013
Cash flows from operating activities:
Net loss	$ (391,839)	$ (374,339)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization expense	29,960	21,245
Stock-based compensation expense	89,024	72,625
Other non-cash based compensation expense	0	5,857
Intangible asset impairment charge	0	412,900
Deferred income taxes	0	(130,661)
Write-down of inventories to net realizable value	0	5,083
Other non-cash items, net	22	7,455
Changes in operating assets and liabilities:
Accounts receivable, net	2,518	(18,462)
Inventories	1,194	6,620
Prepaid expenses and other assets	(17,538)	(18,152)
Accounts payable	7,671	(53,374)
Accrued expenses and other liabilities	(9,459)	4,616
Accrued restructuring expense	(9,369)	(1,276)
Deferred revenues	(5,866)	(6,842)
Net cash used in operating activities	(303,682)	(66,705)
Cash flows from investing activities:
Purchases of marketable securities	(703,977)	(898,706)
Sales and maturities of marketable securities	801,206	830,906
Expenditures for property and equipment	(27,227)	(18,408)
Decrease in restricted cash and cash equivalents	1	31,812
Decrease in restricted cash and cash equivalents (Alios)	0	11,695
Decrease (increase) in deposits	(528)	414
Net cash used in (provided by) investing activities	69,475	(42,287)
Cash flows from financing activities:
Issuances of common stock from employee benefit plans	117,947	207,872
Payments to redeem secured notes (due 2015)	0	(158)
Payments on capital lease obligations	(11,884)	(12,246)
Payments on construction financing lease obligation	(30,292)	(44,115)
Payments returned related to construction financing lease obligation	8,050	0
Net cash provided by (used in) financing activities	83,821	151,353
Effect of changes in exchange rates on cash	1,645	(521)
Net (decrease) increase in cash and cash equivalents	(148,741)	41,840
Cash and cash equivalents—beginning of period	569,299	489,407
Cash and cash equivalents—end of period	420,558	531,247
Supplemental disclosure of cash flow information:
Cash paid for interest	31,933	7,142
Cash paid for income taxes	798	0
Conversion of convertible senior subordinated notes (due 2015) for common stock	0	399,842
Unamortized deferred debt issuance costs exchanged	0	4,230
Capitalization of construction in-process related to construction financing lease obligation	25,564	130,222
Assets acquired under capital lease	$ 8,985	$ 21,576