Stock-based Compensation Expense (Details) (USD $)	12 Months Ended
	Dec. 31, 2013	Dec. 31, 2012	Dec. 31, 2011
Stock-based compensation expense:
Total stock-based compensation expense included in costs and expenses	$ 127,303,000	$ 114,285,000	$ 118,226,000
Less: stock-based compensation expense capitalized to inventories	(1,048,000)	(1,254,000)	(1,042,000)
Weighted-average assumptions for options and ESPP subscriptions granted
Weighted average fair value (in dollars per share)	$ 62.16
Stock Options
Weighted-average assumptions for options and ESPP subscriptions granted
Expected annual dividends	0
Employee Stock Purchase Plan
Weighted-average assumptions for options and ESPP subscriptions granted
Expected stock price volatility (as a percent)	54.69%	46.90%	51.32%
Risk-free interest rate (as a percent)	0.08%	0.16%	0.08%
Expected term of options (in years)	8 months 27 days	8 months 27 days	8 months 19 days
Expected annual dividends	0	0	0
Weighted average fair value (in dollars per share)	$ 21.08	$ 12.90	$ 9.80
Stock options
Stock-based compensation expense:
Total stock-based compensation expense included in costs and expenses	85,067,000	79,047,000	83,098,000
Type of award:
Unrecognized Expense Net of Estimated Forfeitures	141,283,000
Weighted-average Recognition Period (in years)	2 years 6 months 22 days
Weighted-average grant-date fair value, granted (in dollars per share)	$ 25.79	$ 19.72	$ 20.88
Weighted-average assumptions for options and ESPP subscriptions granted
Expected stock price volatility (as a percent)	46.20%	47.93%	49.53%
Risk-free interest rate (as a percent)	1.25%	0.95%	2.09%
Expected term of options (in years)	5 years 9 months 22 days	5 years 9 months 11 days	5 years 8 months 27 days
Expected annual dividends	0	0	0
Restricted stock and restricted stock units
Stock-based compensation expense:
Total stock-based compensation expense included in costs and expenses	36,479,000	29,194,000	30,708,000
Type of award:
Unrecognized Expense Net of Estimated Forfeitures	73,490,000
Weighted-average Recognition Period (in years)	2 years 5 months 19 days
ESPP share issuances
Stock-based compensation expense:
Total stock-based compensation expense included in costs and expenses	6,805,000	7,298,000	5,462,000
Type of award:
Unrecognized Expense Net of Estimated Forfeitures	5,956,000
Weighted-average Recognition Period (in years)	8 months 1 day
Research and development expenses
Stock-based compensation expense:
Total stock-based compensation expense included in costs and expenses	81,467,000	71,533,000	75,574,000
Sales, general and administrative expenses
Stock-based compensation expense:
Total stock-based compensation expense included in costs and expenses	$ 45,836,000	$ 42,752,000	$ 42,652,000