Accrued Expenses and Other Liabilities, Current Portion (Tables)

12 Months Ended

Dec. 31, 2013

Payables and Accruals [Abstract]

Accrued expenses and other current liabilities

Accrued expenses consisted of the following:

	As of December 31,
	2013		2012
	(in thousands)
Product revenue allowances	$	85,510	$	69,936
Payroll and benefits	76,785		62,140
Research, development and commercial contract costs	52,468		63,960
Royalty payable	18,334		29,007
Other	16,241		18,932
Professional fees	10,593		11,226
Taxes payable	8,362		2,182
Unrecognized tax benefits	2,784		4,106
Interest	—		3,395
Total	$	271,077	$	264,884