Stock-based Compensation Expense (Details) (USD $)	12 Months Ended
	Dec. 31, 2012	Dec. 31, 2011	Dec. 31, 2010
Stock-based compensation expense:
Total stock-based compensation expense included in costs and expenses	$ 114,285,000	$ 118,226,000	$ 91,124,000
Less stock-based compensation expense capitalized to inventories	(1,254,000)	(1,042,000)
Weighted-average assumptions for options and ESPP subscriptions granted
Weighted average fair value (in dollars per share)	$ 45.46
Employee Stock Purchase Plan
Weighted-average assumptions for options and ESPP subscriptions granted
Expected stock price volatility (as a percent)	46.90%	51.32%	43.92%
Risk-free interest rate (as a percent)	0.16%	0.08%	0.24%
Expected term (in years)	0.74	0.72	0.71
Expected annual dividends estimate	0	0	0
Weighted average fair value (in dollars per share)	$ 12.90	$ 9.80	$ 10.19
Stock Options:
Weighted-average assumptions for options and ESPP subscriptions granted
Expected annual dividends estimate	0
Stock options
Stock-based compensation expense:
Total stock-based compensation expense included in costs and expenses	79,047,000	83,098,000	64,005,000
Type of award:
Unrecognized Expense, Net of Estimated Forfeitures	156,225,000
Weighted-average Recognition Period (in years)	2.69
Weighted-average assumptions for options and ESPP subscriptions granted
Expected stock price volatility (as a percent)	47.93%	49.53%	52.17%
Risk-free interest rate (as a percent)	0.95%	2.09%	2.44%
Expected term (in years)	5.78	5.74	5.71
Expected annual dividends estimate	0	0	0
Weighted-average grant-date fair value, granted (in dollars per share)	$ 19.72	$ 20.88	$ 18.52
Restricted stock and restricted stock units
Stock-based compensation expense:
Total stock-based compensation expense included in costs and expenses	29,194,000	30,708,000	22,960,000
Type of award:
Unrecognized Expense, Net of Estimated Forfeitures	68,094,000
Weighted-average Recognition Period (in years)	2.58
ESPP share issuances
Stock-based compensation expense:
Total stock-based compensation expense included in costs and expenses	7,298,000	5,462,000	4,159,000
Less stock-based compensation expense capitalized to inventories			0
Type of award:
Unrecognized Expense, Net of Estimated Forfeitures	5,661,000
Weighted-average Recognition Period (in years)	0.65
Research and development expenses
Stock-based compensation expense:
Total stock-based compensation expense included in costs and expenses	71,533,000	75,574,000	65,198,000
Sales, general and administrative expenses
Stock-based compensation expense:
Total stock-based compensation expense included in costs and expenses	$ 42,752,000	$ 42,652,000	$ 25,926,000