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Intangible Assets and Goodwill (Details) (USD $)
3 Months Ended 6 Months Ended
Jun. 30, 2012
Jun. 30, 2011
Jun. 30, 2012
Jun. 30, 2011
Dec. 31, 2011
Intangible assets          
Total intangible assets, gross $ 4,030,600,000   $ 4,030,600,000   $ 3,807,500,000
Accumulated Amortization (2,297,600,000)   (2,297,600,000)   (2,199,300,000)
Intangible assets, net 1,732,972,000   1,732,972,000   1,608,191,000
Intangible Assets and Goodwill (Additional Textual) [Abstract]          
Intangible asset recognized to reflect the total of upfront and other time-based milestone payments expected to be made 4,030,600,000   4,030,600,000   3,807,500,000
Intangible Assets and Goodwill (Textual) [Abstract]          
Amortization of acquired intangible assets 52,282,000 55,136,000 98,243,000 108,352,000  
Business acquisition purchase price allocation to IPR&D 219,200,000   219,200,000    
Business acquisition purchase price allocation goodwill amount 51,600,000   51,600,000    
Accumulated impairment losses related to goodwill 0   0    
Maximum [Member]
         
Intangible Assets and Goodwill (Additional Textual) [Abstract]          
Expected future amortization expense, 2013 200,000,000   200,000,000    
Expected future amortization expense, 2014 200,000,000   200,000,000    
Expected future amortization expense, 2015 200,000,000   200,000,000    
Expected future amortization expense, 2016 200,000,000   200,000,000    
Minimum [Member]
         
Intangible Assets and Goodwill (Additional Textual) [Abstract]          
Expected future amortization expense, 2013 130,000,000   130,000,000    
Expected future amortization expense, 2014 130,000,000   130,000,000    
Expected future amortization expense, 2015 130,000,000   130,000,000    
Expected future amortization expense, 2016 130,000,000   130,000,000    
VP1 Protein [Member]
         
Intangible assets          
Total intangible assets, gross 23,100,000   23,100,000   19,200,000
Intangible Assets and Goodwill (Additional Textual) [Abstract]          
Expected usage-based royalties to be earned through 2016 from license agreement     57,500,000    
Intangible asset recognized to reflect the total of upfront and other time-based milestone payments expected to be made 23,100,000   23,100,000   19,200,000
Out-licensed patents [Member]
         
Intangible assets          
Cost 578,000,000   578,000,000   578,000,000
Accumulated Amortization (406,200,000)   (406,200,000)   (391,300,000)
Net 171,800,000   171,800,000   186,700,000
Out-licensed patents [Member] | Maximum [Member]
         
Intangible assets          
Estimated Life, (In Years)     23 years    
Out-licensed patents [Member] | Minimum [Member]
         
Intangible assets          
Estimated Life, (In Years)     13 years    
Core developed technology [Member]
         
Intangible assets          
Cost 3,005,300,000   3,005,300,000   3,005,300,000
Accumulated Amortization (1,880,600,000)   (1,880,600,000)   (1,801,100,000)
Net 1,124,700,000   1,124,700,000   1,204,200,000
Core developed technology [Member] | Maximum [Member]
         
Intangible assets          
Estimated Life, (In Years)     23 years    
Core developed technology [Member] | Minimum [Member]
         
Intangible assets          
Estimated Life, (In Years)     15 years    
In-licensed rights and patents [Member]
         
Intangible assets          
Cost 51,100,000   51,100,000   47,200,000
Accumulated Amortization (8,700,000)   (8,700,000)   (4,800,000)
Net 42,400,000   42,400,000   42,400,000
In-licensed rights and patents [Member] | Maximum [Member]
         
Intangible assets          
Estimated Life, (In Years)     16 years    
In-licensed rights and patents [Member] | Minimum [Member]
         
Intangible assets          
Estimated Life, (In Years)     6 years    
Assembled workforce [Member]
         
Intangible assets          
Estimated Life, (In Years)     4 years    
Cost 2,100,000   2,100,000   2,100,000
Accumulated Amortization (2,100,000)   (2,100,000)   (2,100,000)
In-process research and development [Member]
         
Indefinite-lived Intangible Assets by Major Class [Line Items]          
Estimated Life     Up to 15 years upon commercialization    
Cost and Net 330,100,000   330,100,000   110,900,000
Trademarks and trade names [Member]
         
Indefinite-lived Intangible Assets by Major Class [Line Items]          
Estimated Life     Indefinite    
Cost and Net $ 64,000,000   $ 64,000,000   $ 64,000,000