Intangible Assets and Goodwill (Tables)

3 Months Ended

Mar. 31, 2026

Goodwill and Intangible Assets Disclosure [Abstract]

Intangible assets

Intangible assets, net of accumulated amortization, impairment charges and adjustments are summarized as follows:

		As of March 31, 2026						As of December 31, 2025
(In millions)	Estimated Life	Cost		Accumulated Amortization		Net		Cost		Accumulated Amortization		Net
Completed technology	1-30 years	$	14,078.8	$	(6,824.3)	$	7,254.5	$	14,067.3	$	(6,687.8)	$	7,379.5
In-process research and development	Indefinite until commercialization	1,635.0		—		1,635.0		1,635.0		—		1,635.0
Priority review voucher	Indefinite	100.0		—		100.0		100.0		—		100.0
Trademarks and trade names	Indefinite	64.0		—		64.0		64.0		—		64.0
Total intangible assets		$	15,877.8	$	(6,824.3)	$	9,053.5	$	15,866.3	$	(6,687.8)	$	9,178.5

Estimated future amortization for acquired intangible assets

The estimated future amortization of finite-lived intangible assets for the next five years is expected to be as follows:

(In millions)	As of March 31, 2026
2026 (remaining nine months)	$	400.0
2027	485.0
2028	525.0
2029	575.0
2030	650.0
2031	700.0

Summary of roll forward of the changes in goodwill

The following table provides a roll forward of the changes in our goodwill balance:

(In millions)	As of March 31, 2026
Goodwill, December 31, 2025	$	6,491.1
Other(1)	(2.4)
Goodwill, March 31, 2026	$	6,488.7

(1) Other includes adjustments related to foreign currency exchange rate fluctuations.