Restructuring - Narrative (Details) $ in Millions	12 Months Ended
	Dec. 31, 2025 USD ($) employee	Dec. 31, 2023 USD ($)	Mar. 31, 2025 ft²	Sep. 30, 2023 ft²
Restructuring Cost and Reserve [Line Items]
Operating lease area | ft²			580,000
Reata Pharmaceuticals, Inc
Restructuring Cost and Reserve [Line Items]
Operating lease area | ft²				327,400
Operating lease, contract term				16 years
Minimum
Restructuring Cost and Reserve [Line Items]
Expected cost remaining	$ 320.0
Operating lease, contract term	1 year
2023 Cost Saving Initiatives
Restructuring Cost and Reserve [Line Items]
Expected operating expense reduction		$ 1,000.0
Expected number of positions eliminated | employee	1,400
Reata Integration
Restructuring Cost and Reserve [Line Items]
Expected cost	$ 35.0