Restructuring (Tables)

12 Months Ended

Dec. 31, 2025

Restructuring and Related Activities [Abstract]

Restructuring and related costs

Total charges incurred from our 2023 Fit for Growth program are summarized as follows:

	For the Years Ended December 31,
	2025						2024						2023
(In millions)	Severance Costs		Accelerated Depreciation and Other		Total		Severance Costs		Accelerated Depreciation and Other		Total		Severance Costs		Accelerated Depreciation and Other		Total
Selling, general and administrative	$	—	$	(1.4)	$	(1.4)	$	—	$	13.8	$	13.8	$	—	$	23.3	$	23.3
Research and development	—		10.1		10.1		—		11.7		11.7		—		1.2		1.2
Restructuring charges	48.7		—		48.7		24.2		—		24.2		153.4		34.6		188.0
Total charges	$	48.7	$	8.7	$	57.4	$	24.2	$	25.5	$	49.7	$	153.4	$	59.1	$	212.5

Total charges incurred from our Reata integration are summarized as follows:

	For the Years Ended December 31,
	2025						2024						2023
(In millions)	Severance Costs		Accelerated Depreciation and Other		Total		Severance Costs		Accelerated Depreciation and Other		Total		Severance Costs		Accelerated Depreciation and Other		Total
Selling, general and administrative	$	—	$	6.8	$	6.8	$	—	$	6.3	$	6.3	$	—	$	—	$	—
Research and development	—		14.3		14.3		—		11.9		11.9		—		—		—
Restructuring charges	(0.7)		—		(0.7)		3.4		—		3.4		30.4		—		30.4
Total charges	$	(0.7)	$	21.1	$	20.4	$	3.4	$	18.2	$	21.6	$	30.4	$	—	$	30.4

Schedule of restructuring reserve by type of cost

Charges and spending related to workforce reductions are summarized as follows:

(In millions)	Workforce Reductions
Restructuring reserve, December 31, 2023	$	75.4
Expense	30.2
Payment	(73.8)
Foreign currency and other adjustments	0.1
Restructuring reserve, December 31, 2024	31.9
Expense	48.6
Payment	(61.5)
Foreign currency and other adjustments	(3.2)
Restructuring reserve, December 31, 2025	$	15.8