Other Consolidated Financial Statement Detail - Accrued Expense and Other (Details) - USD ($) $ in Millions	Dec. 31, 2025	Dec. 31, 2024	Dec. 31, 2023	Dec. 31, 2022
Collaborative arrangements and non-collaborative arrangement transactions
Revenue-related reserves for discounts and allowances	$ 1,210.8	$ 1,091.6	$ 1,062.0	$ 1,035.0
Contingent consideration obligations		291.2
Total accrued expense and other	2,802.6	2,807.7
Component of accrued expense and other
Collaborative arrangements and non-collaborative arrangement transactions
Revenue-related reserves for discounts and allowances	1,000.4	937.5
Employee compensation and benefits	375.8	375.8
Collaboration expense	280.0	309.0
Royalties and licensing fees	302.4	190.2
Contingent consideration obligations	0.0	291.2
Other	$ 844.0	$ 704.0