Collaborative and Other Relationships - Sage Therapeutics, Inc. (Details) - USD ($) $ in Millions	3 Months Ended
	Mar. 31, 2025	Mar. 31, 2024	Dec. 31, 2025
Collaborative arrangements and non-collaborative arrangement transactions
Collaboration profit sharing/(loss reimbursement)	$ 58.1	$ 65.6
Share of net profit from sage therapeutics, Percent	50.00%
Sage Therapeutics
Collaborative arrangements and non-collaborative arrangement transactions
Collaboration profit sharing/(loss reimbursement)	$ 10.1	$ 5.0
Forecast | Sage Therapeutics
Collaborative arrangements and non-collaborative arrangement transactions
Potential future milestone payments commitment to third party			$ 75.0