Other Consolidated Financial Statement Detail (Details) - USD ($) $ in Millions	3 Months Ended
	Mar. 31, 2025	Mar. 31, 2024	Dec. 31, 2024
Other Income (Expense), Net
Interest income	$ (23.9)	$ (17.4)
Interest expense	60.0	69.2
(Gains) losses on investments, net	35.6	30.6
Foreign exchange (gains) losses, net	(3.8)	9.4
Other, net	0.5	1.9
Other (income) expense, net	68.4	93.7
Equity Securities, FV-NI, Gain (Loss), Alternative [Abstract]
Net (gains) losses recognized on equity securities	35.6	30.6
Less: Net (gains) losses realized on equity securities	(5.4)	4.9
Net unrealized (gains) losses recognized on equity securities	41.0	$ 25.7
Accrued Expenses and Other
Revenue-related reserves for discounts and allowances	1,170.4		$ 1,091.6
Employee compensation and benefits	192.3		375.8
Collaboration expense	233.1		309.0
Royalties and licensing fees	166.9		190.2
Contingent consideration obligations	294.3		291.2
Other	678.9		704.0
Total accrued expense and other	2,530.7		2,807.7
Component of accrued expenses and other
Accrued Expenses and Other
Revenue-related reserves for discounts and allowances	$ 965.2		$ 937.5