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Intangible Assets and Goodwill - Narrative (Details) - USD ($)
3 Months Ended
Mar. 31, 2025
Mar. 31, 2024
Dec. 31, 2024
Jul. 02, 2024
Sep. 30, 2023
Goodwill [Line Items]          
Amortization and impairment of acquired intangible assets $ 111,800,000 $ 78,300,000      
Impairment of intangible assets   $ 0      
Accumulated impairment losses related to goodwill $ 0        
Minimum          
Goodwill [Line Items]          
Estimated life (in years) 2 years        
Maximum          
Goodwill [Line Items]          
Estimated life (in years) 31 years        
Acquired and in-licensed rights and patents          
Goodwill [Line Items]          
Weighted-Average remaining useful life 12 years        
Reata Pharmaceuticals, Inc | Priority review voucher          
Goodwill [Line Items]          
Intangible assets:         $ 100,000,000
Human Immunology Biosciences          
Goodwill [Line Items]          
Intangible assets:       $ 1,600,000,000  
Human Immunology Biosciences | In-process research and development          
Goodwill [Line Items]          
Intangible assets: $ 1,600,000,000   $ 1,600,000,000