Restructuring, Business Transformation and Other Cost Saving Initiatives - FIt for Growth Initiative (Details) - USD ($) $ in Millions	3 Months Ended
	Mar. 31, 2025	Mar. 31, 2024
Restructuring Cost and Reserve [Line Items]
Restructuring charges	$ 35.3	$ 11.5
2023 Cost Saving Initiatives
Restructuring Cost and Reserve [Line Items]
Severance Costs	35.3	9.3
Accelerated Depreciation and Other Costs	1.2	6.3
Restructuring charges	36.5	15.6
Reata Integration
Restructuring Cost and Reserve [Line Items]
Severance Costs	(0.2)	2.2
Accelerated Depreciation and Other Costs	4.1	4.5
Restructuring charges	3.9	6.7
Selling, general and administrative | 2023 Cost Saving Initiatives
Restructuring Cost and Reserve [Line Items]
Severance Costs	0.0	0.0
Accelerated Depreciation and Other Costs	(3.9)	1.4
Restructuring charges	(3.9)	1.4
Selling, general and administrative | Reata Integration
Restructuring Cost and Reserve [Line Items]
Severance Costs	0.0	0.0
Accelerated Depreciation and Other Costs	1.8	1.8
Restructuring charges	1.8	1.8
Research and development | 2023 Cost Saving Initiatives
Restructuring Cost and Reserve [Line Items]
Severance Costs	0.0	0.0
Accelerated Depreciation and Other Costs	5.1	4.9
Restructuring charges	5.1	4.9
Research and development | Reata Integration
Restructuring Cost and Reserve [Line Items]
Severance Costs	0.0	0.0
Accelerated Depreciation and Other Costs	2.3	2.7
Restructuring charges	2.3	2.7
Restructuring charges | 2023 Cost Saving Initiatives
Restructuring Cost and Reserve [Line Items]
Severance Costs	35.3	9.3
Accelerated Depreciation and Other Costs	0.0	0.0
Restructuring charges	35.3	9.3
Restructuring charges | Reata Integration
Restructuring Cost and Reserve [Line Items]
Severance Costs	(0.2)	2.2
Accelerated Depreciation and Other Costs	0.0	0.0
Restructuring charges	$ (0.2)	$ 2.2