Property, Plant and Equipment - Narrative (Details) ft² in Thousands, $ in Millions	1 Months Ended	3 Months Ended	12 Months Ended
	Sep. 30, 2022 USD ($)	Mar. 31, 2024 USD ($)	Dec. 31, 2024 USD ($) ft²	Dec. 31, 2023 USD ($)	Dec. 31, 2022 USD ($)
Property, Plant and Equipment [Line Items]
Depreciation expense			$ 286.7	$ 254.2	$ 272.4
Interest costs capitalized			3.2	21.7	17.1
Construction in progress			308.4	975.4
Proceeds from sale of priority review voucher, net			88.6	0.0	0.0
Gain on sale of building, net			0.0	0.0	$ 503.7
Property, plant and equipment, net			3,181.3	3,309.7
125 Broadway Building
Property, Plant and Equipment [Line Items]
Proceeds from sale of priority review voucher, net	$ 603.0
Tenant allowance	10.8
Gain on sale of building, net	$ 503.7
Property, plant and equipment, net			79.2
125 Broadway Building | Buildings
Property, Plant and Equipment [Line Items]
Property, plant and equipment, net			72.6
125 Broadway Building | Land
Property, Plant and Equipment [Line Items]
Property, plant and equipment, net			1.6
125 Broadway Building | Machinery and Equipment
Property, Plant and Equipment [Line Items]
Property, plant and equipment, net			$ 5.0
Solothurn, Switzerland
Property, Plant and Equipment [Line Items]
Construction in progress				$ 728.8
Property, plant and equipment, additions		$ 717.3
Biologics Manufacturing | Solothurn, Switzerland
Property, Plant and Equipment [Line Items]
Number of square feet | ft²			393
Warehouse, Utilities and Support Space | Solothurn, Switzerland
Property, Plant and Equipment [Line Items]
Number of square feet | ft²			290
Administrative Space | Solothurn, Switzerland
Property, Plant and Equipment [Line Items]
Number of square feet | ft²			51