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Fair Value Measurements - Summary of Fair and Carrying Value of Debt Instruments (Details) - USD ($)
$ in Millions
1 Months Ended
Sep. 30, 2023
Dec. 31, 2024
Dec. 31, 2023
Feb. 28, 2021
Dec. 31, 2020
Debt Instrument          
Interest rate on senior notes   3.625%      
Senior Notes          
Debt Instrument          
Notes payable, fair value   $ 5,437.2 $ 6,287.7    
2023 Term Loan 364-day tranche | Senior Notes          
Debt Instrument          
Notes payable, current, fair value disclosure   $ 0.0 150.0    
4.050% Senior Notes due September 15, 2025          
Debt Instrument          
Interest rate on senior notes   4.05%      
4.050% Senior Notes due September 15, 2025 | Senior Notes          
Debt Instrument          
Notes payable, current, fair value disclosure   $ 1,741.0 0.0    
Interest rate on senior notes   4.05%      
Notes payable, fair value   $ 0.0 1,721.5    
Current portion of notes payable and term loan | Senior Notes          
Debt Instrument          
Notes payable, current, fair value disclosure   1,741.0 150.0    
2023 Term Loan three-year tranche | Senior Notes          
Debt Instrument          
Notes payable, fair value   $ 0.0 500.0    
2.250% Senior Notes due May 1, 2030          
Debt Instrument          
Interest rate on senior notes   2.25%      
2.250% Senior Notes due May 1, 2030 | Senior Notes          
Debt Instrument          
Interest rate on senior notes         2.25%
Notes payable, fair value   $ 1,295.6 1,279.3    
5.200% Senior Notes due September 15, 2045          
Debt Instrument          
Interest rate on senior notes   5.20%      
5.200% Senior Notes due September 15, 2045 | Senior Notes          
Debt Instrument          
Interest rate on senior notes   5.20%      
Notes payable, fair value   $ 1,008.0 1,089.7    
3.150% Senior Notes due May 1, 2050          
Debt Instrument          
Interest rate on senior notes   3.15%      
3.150% Senior Notes due May 1, 2050 | Senior Notes          
Debt Instrument          
Interest rate on senior notes         3.15%
Notes payable, fair value   $ 943.7 1,049.0    
3.250% Senior Notes due February 15, 2051          
Debt Instrument          
Interest rate on senior notes   3.25%      
3.250% Senior Notes due February 15, 2051 | Senior Notes          
Debt Instrument          
Interest rate on senior notes       3.25%  
Notes payable, fair value   $ 448.9 498.2    
Non-current portion of notes payable and term loan | Senior Notes          
Debt Instrument          
Notes payable, fair value   $ 3,696.2 $ 6,137.7    
2023 Term Loan | Line of Credit | Reata Pharmaceuticals, Inc          
Debt Instrument          
Proceeds from long-term lines of credit $ 1,000.0        
2023 Term Loan | Line of Credit | Reata Pharmaceuticals, Inc | 2023 Term Loan 364-day tranche          
Debt Instrument          
Proceeds from long-term lines of credit 500.0        
2023 Term Loan | Line of Credit | Reata Pharmaceuticals, Inc | 2023 Term Loan three-year tranche          
Debt Instrument          
Proceeds from long-term lines of credit $ 500.0