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Revenue - Narrative (Details)
$ in Millions
3 Months Ended 12 Months Ended
Jun. 30, 2020
USD ($)
payment
Dec. 31, 2024
USD ($)
wholesaler
Dec. 31, 2023
USD ($)
Dec. 31, 2022
USD ($)
Jul. 31, 2023
Disaggregation of Revenue [Line Items]          
Number of wholesalers | wholesaler   2      
Percentage of total revenues   18.10% 17.20% 16.70%  
Revenue   $ 9,675.9 $ 9,835.6 $ 10,173.4  
Contract manufacturing revenue          
Disaggregation of Revenue [Line Items]          
Revenue   $ 592.1 848.2 417.7  
Remaining performance obligation, amount $ 500.0        
Remaining performance obligation, number of payments | payment 3        
LEQEMBI Collaboration          
Disaggregation of Revenue [Line Items]          
Share of non-controling interest recognized   50.00%     50.00%
Alzheimer's collaboration revenue          
Disaggregation of Revenue [Line Items]          
Revenue   $ 59.9 $ 0.0 $ 0.0  
Distributor One          
Disaggregation of Revenue [Line Items]          
Percentage receivables of wholesale distributor accounted in consolidated receivables   27.20% 24.60%    
Distributor Two          
Disaggregation of Revenue [Line Items]          
Percentage receivables of wholesale distributor accounted in consolidated receivables   11.70% 11.60%    
Distributor One          
Disaggregation of Revenue [Line Items]          
Percentage of revenue from major distributors   25.90% 27.00% 26.80%  
Distributor Two          
Disaggregation of Revenue [Line Items]          
Percentage of revenue from major distributors   13.40% 9.90% 11.10%