Restructuring, Business Transformation and Other Cost Saving Initiatives - Fit for Growth Initiative (Details) - USD ($) $ in Millions	12 Months Ended
	Dec. 31, 2024	Dec. 31, 2023	Dec. 31, 2022
Restructuring Cost and Reserve [Line Items]
Restructuring charges	$ 30.2	$ 218.8	$ 131.1
2023 Cost Saving Initiatives
Restructuring Cost and Reserve [Line Items]
Severance Costs	24.2	153.4
Accelerated Depreciation and Other Costs	25.5	59.1
Restructuring charges	49.7	212.5
2023 Cost Saving Initiatives | Selling, general and administrative
Restructuring Cost and Reserve [Line Items]
Severance Costs	0.0	0.0
Accelerated Depreciation and Other Costs	13.8	23.3
Restructuring charges	13.8	23.3
2023 Cost Saving Initiatives | Research and development
Restructuring Cost and Reserve [Line Items]
Severance Costs	0.0	0.0
Accelerated Depreciation and Other Costs	11.7	1.2
Restructuring charges	11.7	1.2
2023 Cost Saving Initiatives | Restructuring charges
Restructuring Cost and Reserve [Line Items]
Severance Costs	24.2	153.4
Accelerated Depreciation and Other Costs	0.0	34.6
Restructuring charges	24.2	188.0
Reata Integration
Restructuring Cost and Reserve [Line Items]
Severance Costs	3.4	30.4
Accelerated Depreciation and Other Costs	18.2	0.0
Restructuring charges	21.6	30.4
Reata Integration | Selling, general and administrative
Restructuring Cost and Reserve [Line Items]
Severance Costs	0.0	0.0
Accelerated Depreciation and Other Costs	6.3	0.0
Restructuring charges	6.3	0.0
Reata Integration | Research and development
Restructuring Cost and Reserve [Line Items]
Severance Costs	0.0	0.0
Accelerated Depreciation and Other Costs	11.9	0.0
Restructuring charges	11.9	0.0
Reata Integration | Restructuring charges
Restructuring Cost and Reserve [Line Items]
Severance Costs	3.4	30.4
Accelerated Depreciation and Other Costs	0.0	0.0
Restructuring charges	$ 3.4	$ 30.4