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Collaborative and Other Relationships - ADUHELM Collaboration Agreement (Details) - USD ($)
$ in Millions
3 Months Ended 12 Months Ended
Mar. 31, 2022
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2019
Collaborative arrangements and non-collaborative arrangement transactions            
Royalty cost of sales   $ 2,310.4 $ 2,533.4 $ 2,278.3    
Income (loss) from equity method investments   0.0 0.0 2.6    
ADUHELM            
Collaborative arrangements and non-collaborative arrangement transactions            
Royalty cost of sales $ 275.0          
Income (loss) from equity method investments       111.0    
Eisai            
Collaborative arrangements and non-collaborative arrangement transactions            
Amounts receivable   16.7 1.4      
Amounts payable   $ 138.0 $ 118.4      
Eisai | Milestone Payments            
Collaborative arrangements and non-collaborative arrangement transactions            
Percentage of future development costs 45.00%       45.00% 45.00%
Eisai | Collaboration profit sharing            
Collaborative arrangements and non-collaborative arrangement transactions            
Recognized net reductions to operating expense       224.7    
Eisai | ADUHELM | Inventory, Idle Capacity Charges And Contractual Commitments            
Collaborative arrangements and non-collaborative arrangement transactions            
Recognized net reductions to operating expense       $ 197.0