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Collaborative and Other Relationships - Eisai (Details) - USD ($)
$ in Millions
1 Months Ended 12 Months Ended
Mar. 31, 2022
Feb. 28, 2022
Dec. 31, 2024
Dec. 31, 2022
Dec. 31, 2023
Jul. 31, 2023
Mar. 31, 2023
LEQEMBI Collaboration              
Collaborative arrangements and non-collaborative arrangement transactions              
Share of non-controling interest recognized     50.00%     50.00%  
ADUHELM | Maximum              
Collaborative arrangements and non-collaborative arrangement transactions              
Research and development expense       $ 335.0      
Eisai              
Collaborative arrangements and non-collaborative arrangement transactions              
Accrued payment to termination agreement             $ 31.0
Payments made to termination agreement         $ 16.0    
Related cost-sharing reduction (as a percentage)     80.00%        
Eisai | LEQEMBI Collaboration              
Collaborative arrangements and non-collaborative arrangement transactions              
Term of collaboration agreement 10 years 5 years