Other Consolidated Financial Statement Detail - Accrued Expense and Other (Details) - USD ($) $ in Millions	Dec. 31, 2024	Dec. 31, 2023	Dec. 31, 2022	Dec. 31, 2021
SEC Schedule, 12-09, Valuation and Qualifying Accounts Disclosure [Line Items]
Revenue-related reserves for discounts and allowances	$ 1,091.6	$ 1,062.0	$ 1,035.0	$ 935.3
Current portion of contingent consideration obligations	291.2
Total accrued expense and other	2,807.7	2,623.6
Component of accrued expense and other
SEC Schedule, 12-09, Valuation and Qualifying Accounts Disclosure [Line Items]
Revenue-related reserves for discounts and allowances	937.5	926.5
Employee compensation and benefits	375.8	335.1
Collaboration expense	309.0	214.6
Royalties and licensing fees	190.2	191.5
Current portion of contingent consideration obligations	291.2	0.0
Other	$ 704.0	$ 955.9