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Indebtedness - Narrative (Details) - USD ($)
1 Months Ended 12 Months Ended
Sep. 26, 2023
Aug. 31, 2024
Sep. 30, 2023
Jul. 31, 2022
Dec. 31, 2024
Mar. 31, 2024
Sep. 15, 2022
Feb. 28, 2021
Dec. 31, 2020
Sep. 15, 2015
Debt Instrument                    
Senior notes aggregate principal amount                   $ 1,000,000,000
Interest rate on senior notes         3.625%          
Redemption rate             99.92%      
Aggregate principal amount, debt converted       $ 2,400,000            
Revolving Credit Facility                    
Debt Instrument                    
Senior unsecured revolving credit facility maximum borrowing capacity   $ 1,500,000,000                
Debt instrument, term   5 years                
Outstanding borrowings         $ 0          
2.250% Senior Notes due May 1, 2030                    
Debt Instrument                    
Interest rate on senior notes         2.25%          
3.150% Senior Notes due May 1, 2050                    
Debt Instrument                    
Interest rate on senior notes         3.15%          
2015 Senior Notes                    
Debt Instrument                    
Redemptions percentage of 2015 notes         100.00%          
Redemption percentage for change in control provision         101.00%          
4.050% Senior Notes due September 15, 2025                    
Debt Instrument                    
Interest rate on senior notes         4.05%          
5.200% Senior Notes due September 15, 2045                    
Debt Instrument                    
Interest rate on senior notes         5.20%          
3.250% Senior Notes due February 15, 2051                    
Debt Instrument                    
Interest rate on senior notes         3.25%          
Line of Credit | 2023 Term Loan                    
Debt Instrument                    
Senior unsecured revolving credit facility maximum borrowing capacity     $ 1,500,000,000              
Unused borrowing capacity, amount     500,000,000              
Line of Credit | 2023 Term Loan | Reata Pharmaceuticals, Inc                    
Debt Instrument                    
Proceeds from long-term lines of credit     1,000,000,000              
Line of Credit | 2023 Term Loan | 2023 Term Loan three-year tranche | Reata Pharmaceuticals, Inc                    
Debt Instrument                    
Proceeds from long-term lines of credit     $ 500,000,000              
Line of Credit | 2023 Term Loan | Floating Rate 364-Day Tranche                    
Debt Instrument                    
Senior unsecured revolving credit facility maximum borrowing capacity           $ 150,000,000        
Repayments of short-term debt, maturing in more than three months $ 350,000,000                  
Line of Credit | 2023 Term Loan | Term Loan 2023 Three-Year Tranche                    
Debt Instrument                    
Senior unsecured revolving credit facility maximum borrowing capacity           250,000,000        
Line of Credit | The Credit Facility Floating Rate Three-Year Tranche | Floating Rate 364-Day Tranche                    
Debt Instrument                    
Senior unsecured revolving credit facility maximum borrowing capacity           $ 250,000,000.0        
Senior Notes | 2020 Senior Notes                    
Debt Instrument                    
Redemptions percentage of 2015 notes         100.00%          
Redemption percentage for change in control provision         101.00%          
Costs associated with the senior notes offerings         $ 24,400,000          
Senior Notes | 2.250% Senior Notes due May 1, 2030                    
Debt Instrument                    
Senior notes aggregate principal amount                 $ 1,500,000,000  
Interest rate on senior notes                 2.25%  
Redemption percentage par value of senior notes                 99.973%  
Senior Notes | 3.150% Senior Notes due May 1, 2050                    
Debt Instrument                    
Senior notes aggregate principal amount                 $ 1,500,000,000  
Interest rate on senior notes                 3.15%  
Redemption percentage par value of senior notes                 99.174%  
Senior Notes | 2015 Senior Notes                    
Debt Instrument                    
Costs associated with the senior notes offerings         47,500,000          
Debt issuance costs, net         23,600,000          
Senior Notes | 4.050% Senior Notes due September 15, 2025                    
Debt Instrument                    
Senior notes aggregate principal amount         $ 1,750,000,000          
Interest rate on senior notes         4.05%          
Redemption percentage par value of senior notes         99.764%          
Senior Notes | 5.200% Senior Notes due September 15, 2045                    
Debt Instrument                    
Senior notes aggregate principal amount         $ 1,120,000,000          
Interest rate on senior notes         5.20%          
Redemption percentage par value of senior notes         99.294%          
Senior Notes | 2021 Senior Notes                    
Debt Instrument                    
Redemptions percentage of 2015 notes         100.00%          
Redemption percentage for change in control provision         101.00%          
Costs associated with the senior notes offerings         $ 5,400,000          
Senior Notes | 3.250% Senior Notes due February 15, 2051                    
Debt Instrument                    
Senior notes aggregate principal amount               $ 700,700,000    
Interest rate on senior notes               3.25%    
Redemption percentage par value of senior notes               99.298%