Fair Value Measurements - Debt Instruments (Details) - USD ($) $ in Thousands	Sep. 30, 2024	Dec. 31, 2023	Sep. 26, 2023
Debt Instrument [Line Items]
Notes payable, fair value	$ 5,683,500	$ 6,287,700
Current portion notes payable and term loan	1,748,100	150,000
Notes payable	6,293,900	6,938,200
Senior Notes
Debt Instrument [Line Items]
Notes payable, current, fair value disclosure	1,739,900	150,000
Current portion notes payable and term loan	1,748,100	150,000
4.050% Senior Notes due 2025
Debt Instrument [Line Items]
Notes payable, fair value		1,721,500
4.050% Senior Notes due 2025 | Senior Notes
Debt Instrument [Line Items]
Notes payable, current, fair value disclosure	1,739,900	0
Notes payable, fair value	0
Current portion notes payable and term loan	1,748,100	0
Notes payable	0	1,746,600
2.25% Senior Notes due May 1, 2030
Debt Instrument [Line Items]
Notes payable, fair value		1,279,300
2.25% Senior Notes due May 1, 2030 | Senior Notes
Debt Instrument [Line Items]
Notes payable, fair value	1,339,400
Notes payable	1,494,500	1,493,800
5.200% Senior Notes due 2045
Debt Instrument [Line Items]
Notes payable, fair value		1,089,700
5.200% Senior Notes due 2045 | Senior Notes
Debt Instrument [Line Items]
Notes payable, fair value	1,079,200
Notes payable	1,101,000	1,100,700
3.250% Senior Notes, Due February 15, 2051
Debt Instrument [Line Items]
Notes payable, fair value		498,200
3.250% Senior Notes, Due February 15, 2051 | Senior Notes
Debt Instrument [Line Items]
Notes payable, fair value	490,900
Notes payable	475,500	472,800
3.150% Senior Notes due May 1, 2050
Debt Instrument [Line Items]
Notes payable, fair value		1,049,000
3.150% Senior Notes due May 1, 2050 | Senior Notes
Debt Instrument [Line Items]
Notes payable, fair value	1,034,100
Notes payable	1,474,800	1,474,300
2023 Term Loan Three-Year Tranche | Senior Notes
Debt Instrument [Line Items]
Notes payable, fair value	0	500,000
Notes payable	0	500,000
Non-Current Portion Of Notes Payable And Term Loan | Senior Notes
Debt Instrument [Line Items]
Notes payable, fair value	3,943,600	6,137,700
Notes payable	4,545,800	6,788,200
The Credit Facility | Line of Credit
Debt Instrument [Line Items]
Line of credit facility, maximum borrowing capacity			$ 1,500,000
The Credit Facility | Line of Credit | Reata Pharmaceuticals, Inc | Secured Debt
Debt Instrument [Line Items]
Long-term debt, gross			1,000,000
Credit Facility Floating Rate 364-Day Tranche | Line of Credit
Debt Instrument [Line Items]
Line of credit facility, maximum borrowing capacity			500,000
The Credit Facility Floating Rate Three-Year Tranche | Senior Notes
Debt Instrument [Line Items]
Notes payable, current, fair value disclosure	0	150,000
Current portion notes payable and term loan	$ 0	$ 150,000
The Credit Facility Floating Rate Three-Year Tranche | Line of Credit
Debt Instrument [Line Items]
Line of credit facility, maximum borrowing capacity			$ 500,000