Intangible Assets and Goodwill - Narrative (Details) - USD ($)	3 Months Ended		9 Months Ended
	Sep. 30, 2024	Sep. 30, 2023	Sep. 30, 2024	Sep. 30, 2023	Jul. 02, 2024	Sep. 26, 2023
Goodwill [Line Items]
Amortization and impairment of acquired intangible assets	$ 130,300,000	$ 60,900,000	$ 295,500,000	$ 164,000,000.0
Impairment of intangible assets	20,200,000	0	20,200,000	0
Accumulated impairment losses related to goodwill	$ 0		$ 0
Acquired and in-licensed rights and patents
Goodwill [Line Items]
Weighted-Average remaining useful life	13 years		13 years
Acquired and in-licensed rights and patents | Minimum
Goodwill [Line Items]
Estimated life (in years)	2 years		2 years
Acquired and in-licensed rights and patents | Maximum
Goodwill [Line Items]
Estimated life (in years)	21 years		21 years
Developed technology and other
Goodwill [Line Items]
Weighted-Average remaining useful life	10 years		10 years
Developed technology and other | Minimum
Goodwill [Line Items]
Estimated life (in years)	13 years		13 years
Developed technology and other | Maximum
Goodwill [Line Items]
Estimated life (in years)	31 years		31 years
Completed Technology | Minimum
Goodwill [Line Items]
Estimated life (in years)	2 years		2 years
Completed Technology | Maximum
Goodwill [Line Items]
Estimated life (in years)	31 years		31 years
Reata Pharmaceuticals, Inc
Goodwill [Line Items]
Impairment of intangible assets	$ 110,100,000	$ 60,900,000	$ 275,300,000	$ 164,000,000.0
Reata Pharmaceuticals, Inc | In-process research and development
Goodwill [Line Items]
Intangible assets:	2,300,000,000		2,300,000,000			$ 2,300,000,000
Reata Pharmaceuticals, Inc | Completed technology for SKYCLARYS (U.S.)
Goodwill [Line Items]
Intangible assets:	4,200,000,000		4,200,000,000			4,200,000,000
Reata Pharmaceuticals, Inc | Priority review voucher
Goodwill [Line Items]
Intangible assets:	100,000,000.0		100,000,000.0			$ 100,000,000
Human Immunology Biosciences
Goodwill [Line Items]
Intangible assets:					$ 1,600,000,000
Human Immunology Biosciences | In-process research and development
Goodwill [Line Items]
Intangible assets:	$ 1,600,000,000		$ 1,600,000,000