Intangible Assets and Goodwill - Summary of Intangible Assets (Details) - USD ($) $ in Millions	Sep. 30, 2024	Dec. 31, 2023
Finite-Lived Intangible Assets, Net [Abstract]
Finite-Lived Intangible Assets, Gross	$ 14,101.5	$ 11,728.8
Accumulated Amortization	(6,142.9)	(5,869.8)
Net	7,958.6	5,859.0
Intangible Assets, Net (Excluding Goodwill) [Abstract]
Cost	15,948.4	14,232.8
Accumulated Amortization	6,142.9	5,869.8
Net	9,805.5	8,363.0
In-process research and development
Indefinite-Lived Intangible Assets [Line Items]
Cost and net	1,682.9	2,340.0
Priority review voucher
Indefinite-Lived Intangible Assets [Line Items]
Cost and net	100.0	100.0
Trademarks and trade names
Indefinite-Lived Intangible Assets [Line Items]
Cost and net	64.0	64.0
Acquired and in-licensed rights and patents
Finite-Lived Intangible Assets, Net [Abstract]
Finite-Lived Intangible Assets, Gross	10,552.9	8,180.2
Accumulated Amortization	(2,697.9)	(2,440.7)
Net	7,855.0	5,739.5
Intangible Assets, Net (Excluding Goodwill) [Abstract]
Accumulated Amortization	$ 2,697.9	2,440.7
Acquired and in-licensed rights and patents | Minimum
Finite-Lived Intangible Assets [Line Items]
Estimated life (in years)	2 years
Acquired and in-licensed rights and patents | Maximum
Finite-Lived Intangible Assets [Line Items]
Estimated life (in years)	21 years
Developed technology and other
Finite-Lived Intangible Assets, Net [Abstract]
Finite-Lived Intangible Assets, Gross	$ 3,548.6	3,548.6
Accumulated Amortization	(3,445.0)	(3,429.1)
Net	103.6	119.5
Intangible Assets, Net (Excluding Goodwill) [Abstract]
Accumulated Amortization	$ 3,445.0	$ 3,429.1
Developed technology and other | Minimum
Finite-Lived Intangible Assets [Line Items]
Estimated life (in years)	13 years
Developed technology and other | Maximum
Finite-Lived Intangible Assets [Line Items]
Estimated life (in years)	31 years