Restructuring, Business Transformation and Other Cost Saving Initiatives - FIt for Growth Initiative (Details) - USD ($) $ in Millions	3 Months Ended		9 Months Ended
	Sep. 30, 2024	Sep. 30, 2023	Sep. 30, 2024	Sep. 30, 2023
Restructuring Cost and Reserve [Line Items]
Restructuring charges	$ 6.8	$ 76.0	$ 24.9	$ 120.0
2023 Cost Saving Initiatives
Restructuring Cost and Reserve [Line Items]
Severance Costs	4.6	37.7	20.2	62.6
Accelerated Depreciation and Other Costs	12.6	23.4	23.1	51.9
Restructuring charges	17.2	61.1	43.3	114.5
Reata Integration
Restructuring Cost and Reserve [Line Items]
Severance Costs	0.7	21.0	3.2	21.0
Accelerated Depreciation and Other Costs	4.5	0.0	13.8	0.0
Restructuring charges	5.2	21.0	17.0	21.0
Selling, general and administrative | 2023 Cost Saving Initiatives
Restructuring Cost and Reserve [Line Items]
Severance Costs	0.0	0.0	0.0	0.0
Accelerated Depreciation and Other Costs	9.1	5.9	12.5	17.4
Restructuring charges	9.1	5.9	12.5	17.4
Selling, general and administrative | Reata Integration
Restructuring Cost and Reserve [Line Items]
Severance Costs	0.0	0.0	0.0	0.0
Accelerated Depreciation and Other Costs	1.6	0.0	4.9	0.0
Restructuring charges	1.6	0.0	4.9	0.0
Research and development | 2023 Cost Saving Initiatives
Restructuring Cost and Reserve [Line Items]
Severance Costs	0.0	0.0	0.0	0.0
Accelerated Depreciation and Other Costs	3.5	0.2	10.6	0.7
Restructuring charges	3.5	0.2	10.6	0.7
Research and development | Reata Integration
Restructuring Cost and Reserve [Line Items]
Severance Costs	0.0	0.0	0.0	0.0
Accelerated Depreciation and Other Costs	2.9	0.0	8.9	0.0
Restructuring charges	2.9	0.0	8.9	0.0
Restructuring charges | 2023 Cost Saving Initiatives
Restructuring Cost and Reserve [Line Items]
Severance Costs	4.6	37.7	20.2	62.6
Accelerated Depreciation and Other Costs	0.0	17.3	0.0	33.8
Restructuring charges	4.6	55.0	20.2	96.4
Restructuring charges | Reata Integration
Restructuring Cost and Reserve [Line Items]
Severance Costs	0.7	21.0	3.2	21.0
Accelerated Depreciation and Other Costs	0.0	0.0	0.0	0.0
Restructuring charges	$ 0.7	$ 21.0	$ 3.2	$ 21.0