Intangible Assets and Goodwill - Narrative (Details) - USD ($)	3 Months Ended
	Mar. 31, 2024	Mar. 31, 2023	Sep. 26, 2023
Goodwill [Line Items]
Accumulated impairment losses related to goodwill	$ 0
Amortization and impairment of acquired intangible assets	$ 78,300,000	$ 50,200,000
Acquired and in-licensed rights and patents
Goodwill [Line Items]
Weighted-Average remaining useful life	12 years
Acquired and in-licensed rights and patents | Minimum
Goodwill [Line Items]
Estimated life (in years)	2 years
Acquired and in-licensed rights and patents | Maximum
Goodwill [Line Items]
Estimated life (in years)	22 years
Developed technology and other
Goodwill [Line Items]
Weighted-Average remaining useful life	10 years
Developed technology and other | Minimum
Goodwill [Line Items]
Estimated life (in years)	13 years
Developed technology and other | Maximum
Goodwill [Line Items]
Estimated life (in years)	31 years
Completed Technology | Minimum
Goodwill [Line Items]
Estimated life (in years)	2 years
Completed Technology | Maximum
Goodwill [Line Items]
Estimated life (in years)	31 years
Reata Pharmaceuticals, Inc | In-process research and development
Goodwill [Line Items]
Intangible assets:	$ 2,300,000,000		$ 2,300,000,000
Reata Pharmaceuticals, Inc | Completed technology for SKYCLARYS (U.S.)
Goodwill [Line Items]
Intangible assets:	4,200,000,000		4,200,000,000
Reata Pharmaceuticals, Inc | Priority review voucher
Goodwill [Line Items]
Intangible assets:	$ 100,000,000.0		$ 100,000,000