Intangible Assets and Goodwill - Summary of Intangible Assets (Details) - USD ($) $ in Millions	Dec. 31, 2023	Dec. 31, 2022
Finite-Lived Intangible Assets, Net [Abstract]
Finite-Lived Intangible Assets, Gross	$ 11,728.8	$ 7,415.3
Accumulated Amortization	(5,869.8)	(5,629.2)
Net	5,859.0	1,786.1
Intangible Assets, Net (Excluding Goodwill) [Abstract]
Cost	14,232.8	7,479.3
Accumulated Amortization	5,869.8	5,629.2
Net	8,363.0	1,850.1
In-process research and development
Indefinite-Lived Intangible Assets [Line Items]
Cost and net	2,340.0	0.0
Priority review voucher
Indefinite-Lived Intangible Assets [Line Items]
Cost and net	100.0	0.0
Trademarks and trade names
Indefinite-Lived Intangible Assets [Line Items]
Cost and net	64.0	64.0
Acquired and in-licensed rights and patents
Finite-Lived Intangible Assets, Net [Abstract]
Finite-Lived Intangible Assets, Gross	8,180.2	3,866.6
Accumulated Amortization	(2,440.7)	(2,219.1)
Net	5,739.5	1,647.5
Intangible Assets, Net (Excluding Goodwill) [Abstract]
Accumulated Amortization	$ 2,440.7	2,219.1
Acquired and in-licensed rights and patents | Minimum
Finite-Lived Intangible Assets [Line Items]
Estimated life (in years)	2 years
Acquired and in-licensed rights and patents | Maximum
Finite-Lived Intangible Assets [Line Items]
Estimated life (in years)	22 years
Developed technology and other
Finite-Lived Intangible Assets, Net [Abstract]
Finite-Lived Intangible Assets, Gross	$ 3,548.6	3,548.7
Accumulated Amortization	(3,429.1)	(3,410.1)
Net	119.5	138.6
Intangible Assets, Net (Excluding Goodwill) [Abstract]
Accumulated Amortization	$ 3,429.1	$ 3,410.1
Developed technology and other | Minimum
Finite-Lived Intangible Assets [Line Items]
Estimated life (in years)	13 years
Developed technology and other | Maximum
Finite-Lived Intangible Assets [Line Items]
Estimated life (in years)	31 years