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Revenue - Revenues by Product (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2023
Dec. 31, 2022
Dec. 31, 2021
Disaggregation of Revenue [Line Items]      
Total product revenue $ 9,835.6 $ 10,173.4 $ 10,981.7
TECFIDERA      
Disaggregation of Revenue [Line Items]      
Total product revenue 1,012.5 1,443.9 1,951.9
VUMERITY      
Disaggregation of Revenue [Line Items]      
Total product revenue 576.3 553.4 410.4
Total Fumarate      
Disaggregation of Revenue [Line Items]      
Total product revenue 1,588.8 1,997.3 2,362.3
AVONEX      
Disaggregation of Revenue [Line Items]      
Total product revenue 811.0 973.5 1,208.7
PLEGRIDY      
Disaggregation of Revenue [Line Items]      
Total product revenue 294.7 331.9 357.4
Total Interferon      
Disaggregation of Revenue [Line Items]      
Total product revenue 1,105.7 1,305.4 1,566.1
TYSABRI      
Disaggregation of Revenue [Line Items]      
Total product revenue 1,876.9 2,030.9 2,063.1
FAMPYRA      
Disaggregation of Revenue [Line Items]      
Total product revenue 90.5 96.6 105.2
Subtotal: Multiple Sclerosis      
Disaggregation of Revenue [Line Items]      
Total product revenue 4,661.9 5,430.2 6,096.7
SPINRAZA      
Disaggregation of Revenue [Line Items]      
Total product revenue 1,741.2 1,793.5 1,905.1
QALSODY      
Disaggregation of Revenue [Line Items]      
Total product revenue 5.9 0.0 0.0
SKYCLARYS      
Disaggregation of Revenue [Line Items]      
Total product revenue 55.9 0.0 0.0
Subtotal: Rare Disease      
Disaggregation of Revenue [Line Items]      
Total product revenue 1,803.0 1,793.5 1,905.1
BENEPALI      
Disaggregation of Revenue [Line Items]      
Total product revenue 438.8 441.0 498.3
IMRALDI      
Disaggregation of Revenue [Line Items]      
Total product revenue 222.1 224.5 233.4
FLIXABI      
Disaggregation of Revenue [Line Items]      
Total product revenue 77.4 81.3 99.4
BYOOVIZ      
Disaggregation of Revenue [Line Items]      
Total product revenue 31.7 4.3 0.0
Subtotal: Biosimilars      
Disaggregation of Revenue [Line Items]      
Total product revenue 770.0 751.1 831.1
Other      
Disaggregation of Revenue [Line Items]      
Total product revenue 11.8 13.0 14.0
Total product revenue      
Disaggregation of Revenue [Line Items]      
Total product revenue 7,246.7 7,987.8 8,846.9
United States | TECFIDERA      
Disaggregation of Revenue [Line Items]      
Total product revenue 263.1 417.7 680.6
United States | VUMERITY      
Disaggregation of Revenue [Line Items]      
Total product revenue 512.1 521.3 408.9
United States | Total Fumarate      
Disaggregation of Revenue [Line Items]      
Total product revenue 775.2 939.0 1,089.5
United States | AVONEX      
Disaggregation of Revenue [Line Items]      
Total product revenue 536.7 649.2 830.2
United States | PLEGRIDY      
Disaggregation of Revenue [Line Items]      
Total product revenue 126.2 148.4 152.9
United States | Total Interferon      
Disaggregation of Revenue [Line Items]      
Total product revenue 662.9 797.6 983.1
United States | TYSABRI      
Disaggregation of Revenue [Line Items]      
Total product revenue 997.9 1,123.4 1,142.2
United States | FAMPYRA      
Disaggregation of Revenue [Line Items]      
Total product revenue 0.0 0.0 0.0
United States | Subtotal: Multiple Sclerosis      
Disaggregation of Revenue [Line Items]      
Total product revenue 2,436.0 2,860.0 3,214.8
United States | SPINRAZA      
Disaggregation of Revenue [Line Items]      
Total product revenue 610.5 600.2 587.9
United States | QALSODY      
Disaggregation of Revenue [Line Items]      
Total product revenue 5.8 0.0 0.0
United States | SKYCLARYS      
Disaggregation of Revenue [Line Items]      
Total product revenue 55.9 0.0 0.0
United States | Subtotal: Rare Disease      
Disaggregation of Revenue [Line Items]      
Total product revenue 672.2 600.2 587.9
United States | BENEPALI      
Disaggregation of Revenue [Line Items]      
Total product revenue 0.0 0.0 0.0
United States | IMRALDI      
Disaggregation of Revenue [Line Items]      
Total product revenue 0.0 0.0 0.0
United States | FLIXABI      
Disaggregation of Revenue [Line Items]      
Total product revenue 0.0 0.0 0.0
United States | BYOOVIZ      
Disaggregation of Revenue [Line Items]      
Total product revenue 29.2 4.3 0.0
United States | Subtotal: Biosimilars      
Disaggregation of Revenue [Line Items]      
Total product revenue 29.2 4.3 0.0
United States | Other      
Disaggregation of Revenue [Line Items]      
Total product revenue 4.0 4.8 3.0
United States | Total product revenue      
Disaggregation of Revenue [Line Items]      
Total product revenue 3,141.4 3,469.3 3,805.7
Rest of World | TECFIDERA      
Disaggregation of Revenue [Line Items]      
Total product revenue 749.4 1,026.2 1,271.3
Rest of World | VUMERITY      
Disaggregation of Revenue [Line Items]      
Total product revenue 64.2 32.1 1.5
Rest of World | Total Fumarate      
Disaggregation of Revenue [Line Items]      
Total product revenue 813.6 1,058.3 1,272.8
Rest of World | AVONEX      
Disaggregation of Revenue [Line Items]      
Total product revenue 274.3 324.3 378.5
Rest of World | PLEGRIDY      
Disaggregation of Revenue [Line Items]      
Total product revenue 168.5 183.5 204.5
Rest of World | Total Interferon      
Disaggregation of Revenue [Line Items]      
Total product revenue 442.8 507.8 583.0
Rest of World | TYSABRI      
Disaggregation of Revenue [Line Items]      
Total product revenue 879.0 907.5 920.9
Rest of World | FAMPYRA      
Disaggregation of Revenue [Line Items]      
Total product revenue 90.5 96.6 105.2
Rest of World | Subtotal: Multiple Sclerosis      
Disaggregation of Revenue [Line Items]      
Total product revenue 2,225.9 2,570.2 2,881.9
Rest of World | SPINRAZA      
Disaggregation of Revenue [Line Items]      
Total product revenue 1,130.7 1,193.3 1,317.2
Rest of World | QALSODY      
Disaggregation of Revenue [Line Items]      
Total product revenue 0.1 0.0 0.0
Rest of World | SKYCLARYS      
Disaggregation of Revenue [Line Items]      
Total product revenue 0.0 0.0 0.0
Rest of World | Subtotal: Rare Disease      
Disaggregation of Revenue [Line Items]      
Total product revenue 1,130.8 1,193.3 1,317.2
Rest of World | BENEPALI      
Disaggregation of Revenue [Line Items]      
Total product revenue 438.8 441.0 498.3
Rest of World | IMRALDI      
Disaggregation of Revenue [Line Items]      
Total product revenue 222.1 224.5 233.4
Rest of World | FLIXABI      
Disaggregation of Revenue [Line Items]      
Total product revenue 77.4 81.3 99.4
Rest of World | BYOOVIZ      
Disaggregation of Revenue [Line Items]      
Total product revenue 2.5 0.0 0.0
Rest of World | Subtotal: Biosimilars      
Disaggregation of Revenue [Line Items]      
Total product revenue 740.8 746.8 831.1
Rest of World | Other      
Disaggregation of Revenue [Line Items]      
Total product revenue 7.8 8.2 11.0
Rest of World | Total product revenue      
Disaggregation of Revenue [Line Items]      
Total product revenue $ 4,105.3 $ 4,518.5 $ 5,041.2