Segment Information - Geographic Information (Details) - USD ($) $ in Millions	12 Months Ended
	Dec. 31, 2023	Dec. 31, 2022	Dec. 31, 2021
Revenue, Major Customer [Line Items]
Revenue	$ 9,835.6	$ 10,173.4	$ 10,981.7
Long-lived assets	3,729.7	3,702.5	3,791.8
U.S.
Revenue, Major Customer [Line Items]
Long-lived assets	1,443.0	1,369.4	1,390.5
Europe
Revenue, Major Customer [Line Items]
Long-lived assets	2,248.0	2,275.8	2,337.8
Germany
Revenue, Major Customer [Line Items]
Long-lived assets	17.5	21.0	25.4
Asia
Revenue, Major Customer [Line Items]
Long-lived assets	8.3	13.7	16.4
Other
Revenue, Major Customer [Line Items]
Long-lived assets	12.9	22.6	21.7
Product revenue, net
Revenue, Major Customer [Line Items]
Revenue	7,246.7	7,987.8	8,846.9
Product revenue, net | U.S.
Revenue, Major Customer [Line Items]
Revenue	3,141.4	3,469.3	3,805.7
Product revenue, net | Europe
Revenue, Major Customer [Line Items]
Revenue	2,127.4	2,401.3	2,626.0
Product revenue, net | Germany
Revenue, Major Customer [Line Items]
Revenue	868.0	926.2	1,162.4
Product revenue, net | Asia
Revenue, Major Customer [Line Items]
Revenue	649.4	672.1	688.0
Product revenue, net | Other
Revenue, Major Customer [Line Items]
Revenue	460.5	518.9	564.8
Revenue from anti-CD20 therapeutic programs
Revenue, Major Customer [Line Items]
Revenue	1,689.6	1,700.5	1,658.5
Revenue from anti-CD20 therapeutic programs | U.S.
Revenue, Major Customer [Line Items]
Revenue	1,618.5	1,636.4	1,596.7
Revenue from anti-CD20 therapeutic programs | Europe
Revenue, Major Customer [Line Items]
Revenue	0.4	0.1	0.0
Revenue from anti-CD20 therapeutic programs | Germany
Revenue, Major Customer [Line Items]
Revenue	0.0	0.0	0.0
Revenue from anti-CD20 therapeutic programs | Asia
Revenue, Major Customer [Line Items]
Revenue	0.0	0.0	0.0
Revenue from anti-CD20 therapeutic programs | Other
Revenue, Major Customer [Line Items]
Revenue	70.7	64.0	61.8
Contract manufacturing, royalty and other revenue
Revenue, Major Customer [Line Items]
Revenue	899.3	485.1	476.3
Contract manufacturing, royalty and other revenue | U.S.
Revenue, Major Customer [Line Items]
Revenue	673.6	425.8	429.9
Contract manufacturing, royalty and other revenue | Europe
Revenue, Major Customer [Line Items]
Revenue	11.7	11.7	9.7
Contract manufacturing, royalty and other revenue | Germany
Revenue, Major Customer [Line Items]
Revenue	0.0	0.0	0.0
Contract manufacturing, royalty and other revenue | Asia
Revenue, Major Customer [Line Items]
Revenue	214.0	47.6	36.7
Contract manufacturing, royalty and other revenue | Other
Revenue, Major Customer [Line Items]
Revenue	$ 0.0	$ 0.0	$ 0.0