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Collaborative and Other Relationships - Summary of Activity Related To Denali Therapeutics (Details) - Research and development - Denali Therapeutics - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2023
Dec. 31, 2022
Dec. 31, 2021
Collaborative arrangements and non-collaborative arrangement transactions      
Expense incurred by the collaboration $ 65.0 $ 75.1 $ 42.5
Expense reflected within statements of income $ 39.0 $ 43.8 $ 25.5