Other Consolidated Financial Statement Detail - Accrued Expense and Other (Details) - USD ($) $ in Millions	Dec. 31, 2023	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
SEC Schedule, 12-09, Valuation and Qualifying Accounts Disclosure [Line Items]
Revenue-related reserves for discounts and allowances	$ 1,062.0	$ 1,035.0	$ 935.3	$ 1,276.0
Reata acquisition-related accrued expense	117.5	0.0
Total accrued expense and other	2,623.6	2,521.4
Component of accrued expense and other
SEC Schedule, 12-09, Valuation and Qualifying Accounts Disclosure [Line Items]
Revenue-related reserves for discounts and allowances	926.5	891.6
Employee compensation and benefits	335.1	395.6
Collaboration expense	214.6	277.9
Royalties and licensing fees	191.5	209.4
Other	$ 838.4	$ 746.9