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Collaborative and Other Relationships - Other Arrangements (Details) - USD ($)
$ in Millions
3 Months Ended 9 Months Ended
Sep. 30, 2023
Sep. 30, 2022
Sep. 30, 2023
Sep. 30, 2022
Collaborative arrangements and non-collaborative arrangement transactions        
Research and development $ 736.3 $ 549.2 $ 1,891.1 $ 1,629.5
Other research and discovery        
Collaborative arrangements and non-collaborative arrangement transactions        
Research and development $ 0.0 $ 14.0 $ 2.8 $ 51.5