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Other Consolidated Financial Statement (Details Textual) - USD ($)
$ in Millions
1 Months Ended 3 Months Ended 9 Months Ended
Sep. 26, 2023
Oct. 31, 2023
Sep. 30, 2023
Sep. 30, 2022
Jun. 30, 2022
Sep. 30, 2023
Sep. 30, 2022
Dec. 31, 2022
Litigation settlement agreement     $ 0.0 $ 0.0 $ 900.0 $ 0.0 $ 900.0  
Net gains recognized on the increase in fair value of equity securities     297.6 (109.3)   268.3 158.1  
Net gains (losses) realized during the period on equity securities     4.4 (0.5)   5.3 0.0  
Other long-term liabilities     747.9     747.9   $ 944.2
Accrued income taxes     393.8     393.8   $ 541.7
Reata Pharmaceuticals, Inc                
Loss on research and development contracts terminated with Eisai $ 300.0              
Total transaction value $ 6,602.9              
Reata Pharmaceuticals, Inc | Subsequent Event                
Total transaction value   $ 980.0            
Ionis, Sangamo, Denali and Sage                
Net gains recognized on the increase in fair value of equity securities     $ 295.6 $ 112.5   $ 265.0 198.0  
Net gains recognized on the decrease in fair value of equity securities             $ 52.2