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Collaborative and Other Relationships - Other Arrangements (Details) - USD ($)
$ in Millions
3 Months Ended 6 Months Ended
Jun. 30, 2023
Jun. 30, 2022
Jun. 30, 2023
Jun. 30, 2022
Collaborative arrangements and non-collaborative arrangement transactions        
Research and development $ 584.2 $ 528.6 $ 1,154.8 $ 1,080.3
Other research and discovery        
Collaborative arrangements and non-collaborative arrangement transactions        
Research and development $ 2.6 $ 18.0 $ 2.8 $ 37.5