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Investments in Variable Interest Entities (Details) - USD ($)
$ in Millions
3 Months Ended
Mar. 31, 2023
Mar. 31, 2022
Dec. 31, 2022
Variable Interest Entity [Line Items]      
(Gain) loss on equity method investments $ 0.0 $ (3.3)  
Percentage of future development costs related to Eisai 45.00%    
Deferred tax assets, unrecognized tax benefit $ 85.0    
Investment in biotechnology companies that are determined to be unconsolidated variable interest entities $ 28.0   $ 27.8
Neurimmune      
Variable Interest Entity [Line Items]      
Collaboration agreement term 12 years    
Research and development costs, percentage 100.00%    
Eisai      
Variable Interest Entity [Line Items]      
Percentage of future development costs related to Eisai   45.00%