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Other Consolidated Financial Statement (Details Textual) - USD ($)
$ in Millions
3 Months Ended
Mar. 31, 2023
Mar. 31, 2022
Dec. 31, 2022
Net gains recognized on the increase in fair value of equity securities $ 76.5 $ 190.9  
Net gains (losses) realized during the period on equity securities 1.6 (0.2)  
Other long-term liabilities 935.5   $ 944.2
Accrued income taxes 552.5   $ 541.7
Ionis, Sangamo, Denali and Sage      
Net gains recognized on the increase in fair value of equity securities $ 100.0 $ 205.5