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Property, Plant and Equipment - Narrative (Details)
ft² in Thousands, $ in Millions
1 Months Ended 12 Months Ended
Sep. 30, 2022
USD ($)
Dec. 31, 2022
USD ($)
ft²
Dec. 31, 2021
USD ($)
Dec. 31, 2020
USD ($)
Jun. 30, 2021
USD ($)
Property, Plant and Equipment [Line Items]          
Depreciation expense   $ 272.4 $ 235.3 $ 201.9  
Interest costs capitalized   17.1 36.3 65.2  
Construction in progress   888.8 770.3    
Property, plant and equipment, gross   5,464.3 5,423.0    
Proceeds from divestiture of Hillerød, Denmark manufacturing operations   0.0 28.1 0.0  
Gain on sale of building   503.7 0.0 $ 0.0  
Property, plant and equipment, net   3,298.6 3,416.4    
125 Broadway Building          
Property, Plant and Equipment [Line Items]          
Proceeds from divestiture of Hillerød, Denmark manufacturing operations $ 603.0        
Tenant allowance 10.8        
Gain on sale of building 503.7        
Property, plant and equipment, net 79.2        
125 Broadway Building | Buildings          
Property, Plant and Equipment [Line Items]          
Property, plant and equipment, net 72.6        
125 Broadway Building | Land          
Property, Plant and Equipment [Line Items]          
Property, plant and equipment, net 1.6        
125 Broadway Building | Machinery and Equipment          
Property, Plant and Equipment [Line Items]          
Property, plant and equipment, net $ 5.0        
Solothurn, Switzerland          
Property, Plant and Equipment [Line Items]          
Construction in progress   $ 711.1 $ 677.0    
Property, plant and equipment, gross         $ 1,200.0
Biologics Manufacturing | Solothurn, Switzerland          
Property, Plant and Equipment [Line Items]          
Number of square feet | ft²   393      
Warehouse, Utilities and Support Space | Solothurn, Switzerland          
Property, Plant and Equipment [Line Items]          
Number of square feet | ft²   290      
Administrative Space | Solothurn, Switzerland          
Property, Plant and Equipment [Line Items]          
Number of square feet | ft²   51