Intangible Assets and Goodwill - Summary of Intangible Assets (Details) - USD ($) $ in Millions	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021
Finite-Lived Intangible Assets [Line Items]
Total intangible assets	$ 7,479.3	$ 7,609.8
Accumulated Amortization	(5,629.2)	(5,388.5)
Total intangible assets	1,850.1	2,221.3
Finite-Lived Intangible Assets, Amortization Expense, Next Twelve Months	215.0
Finite-Lived Intangible Assets, Amortization Expense, Year Two	195.0
Finite-Lived Intangible Assets, Amortization Expense, Year Three	190.0
Finite-Lived Intangible Assets, Amortization Expense, Year Four	175.0
2027	165.0
Out Licensed Patents
Finite-Lived Intangible Assets [Line Items]
Accumulated Amortization	(5,629.2)	(5,388.5)
Net	1,786.1	2,024.6
Finite-Lived Intangible Assets, Gross	$ 7,415.3	7,413.1
Minimum | Out Licensed Patents
Finite-Lived Intangible Assets [Line Items]
Estimated life	4 years
Maximum | Out Licensed Patents
Finite-Lived Intangible Assets [Line Items]
Estimated life	28 years
In-process research and development
Finite-Lived Intangible Assets [Line Items]
Cost and net	$ 0.0	132.7
Accumulated Amortization	0.0	0.0
Trademarks and trade names
Finite-Lived Intangible Assets [Line Items]
Cost and net	64.0	64.0
Accumulated Amortization	$ 0.0	$ 0.0