Segment Information - Geographic Information (Details) - USD ($) $ in Millions	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Revenue, Major Customer [Line Items]
Revenue	$ 10,173.4	$ 10,981.7	$ 13,444.6
Long-lived assets	3,702.5	3,791.8	3,844.8
U.S.
Revenue, Major Customer [Line Items]
Long-lived assets	1,369.4	1,390.5	1,496.3
Europe
Revenue, Major Customer [Line Items]
Long-lived assets	2,275.8	2,337.8	2,290.2
Germany
Revenue, Major Customer [Line Items]
Long-lived assets	21.0	25.4	31.2
Asia
Revenue, Major Customer [Line Items]
Long-lived assets	13.7	16.4	16.2
Other
Revenue, Major Customer [Line Items]
Long-lived assets	22.6	21.7	10.9
Product, net
Revenue, Major Customer [Line Items]
Revenue	7,987.8	8,846.9	10,692.2
Product, net | U.S.
Revenue, Major Customer [Line Items]
Revenue	3,469.3	3,805.7	5,900.1
Product, net | Europe
Revenue, Major Customer [Line Items]
Revenue	2,401.3	2,626.0	2,495.3
Product, net | Germany
Revenue, Major Customer [Line Items]
Revenue	926.2	1,162.4	1,161.1
Product, net | Asia
Revenue, Major Customer [Line Items]
Revenue	672.1	688.0	596.7
Product, net | Other
Revenue, Major Customer [Line Items]
Revenue	518.9	564.8	539.0
Revenue from anti-CD20 therapeutic programs
Revenue, Major Customer [Line Items]
Revenue	1,700.5	1,658.5	1,977.8
Revenue from anti-CD20 therapeutic programs | U.S.
Revenue, Major Customer [Line Items]
Revenue	1,636.4	1,596.7	1,897.4
Revenue from anti-CD20 therapeutic programs | Europe
Revenue, Major Customer [Line Items]
Revenue	0.1	0.0	0.1
Revenue from anti-CD20 therapeutic programs | Germany
Revenue, Major Customer [Line Items]
Revenue	0.0	0.0	0.0
Revenue from anti-CD20 therapeutic programs | Asia
Revenue, Major Customer [Line Items]
Revenue	0.0	0.0	0.0
Revenue from anti-CD20 therapeutic programs | Other
Revenue, Major Customer [Line Items]
Revenue	64.0	61.8	80.3
Other
Revenue, Major Customer [Line Items]
Revenue	485.1	476.3	774.6
Other | U.S.
Revenue, Major Customer [Line Items]
Revenue	425.8	429.9	733.6
Other | Europe
Revenue, Major Customer [Line Items]
Revenue	11.7	9.7	8.0
Other | Germany
Revenue, Major Customer [Line Items]
Revenue	0.0	0.0	0.1
Other | Asia
Revenue, Major Customer [Line Items]
Revenue	47.6	36.7	32.9
Other | Other
Revenue, Major Customer [Line Items]
Revenue	$ 0.0	$ 0.0	$ 0.0