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Investments in Variable Interest Entities (Details) - USD ($)
$ in Millions
3 Months Ended 12 Months Ended
Jun. 30, 2021
Jun. 30, 2020
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Mar. 31, 2022
Variable Interest Entity [Line Items]            
Potential future milestone payments commitment to third party approximately     $ 9,300.0      
Income (loss) from equity method investments     2.6 $ 34.9 $ 3.3  
Deferred tax asset, net       100.0    
Valuation allowance     2,003.3 1,961.3   $ 85.0
Investment in biotechnology companies that are determined to be unconsolidated variable interest entities     27.8 24.6    
ADUHELM            
Variable Interest Entity [Line Items]            
Income (loss) from equity method investments     $ 111.0 30.0    
Neurimmune            
Variable Interest Entity [Line Items]            
Term of collaboration agreement     12 years      
Research and development costs, percentage     100.00%      
Regulatory Milestones            
Variable Interest Entity [Line Items]            
Potential future milestone payments commitment to third party approximately     $ 500.0      
Regulatory Milestones | Neurimmune            
Variable Interest Entity [Line Items]            
Potential future milestone payments commitment to third party approximately   $ 75.0        
Eisai            
Variable Interest Entity [Line Items]            
Income (loss) from equity method investments   $ 33.8 $ 0.0 45.0 $ 33.8  
Eisai | ADUHELM            
Variable Interest Entity [Line Items]            
Income (loss) from equity method investments $ 45.0     $ 59.0    
Eisai | Regulatory Milestones | Neurimmune | ADUHELM            
Variable Interest Entity [Line Items]            
Potential future milestone payments commitment to third party approximately $ 100.0