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Collaborative and Other Relationships - Summary of Activity Related to Sage Therapeutics (Details) - Sage Therapeutics - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Research and development      
Collaborative arrangements and non-collaborative arrangement transactions      
Expense incurred by the collaboration $ 173.3 $ 167.7 $ 0.0
Expense reflected within statements of income 86.7 83.8 0.0
Selling, general and administrative      
Collaborative arrangements and non-collaborative arrangement transactions      
Expense incurred by the collaboration 109.9 36.4 0.0
Expense reflected within statements of income $ 55.0 $ 18.2 $ 0.0