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Inventory - Components of Inventory (Details) - USD ($)
$ in Millions
Sep. 30, 2022
Dec. 31, 2021
Inventory [Line Items]    
Raw materials $ 394.2 $ 349.6
Work in process 771.0 814.0
Finished goods 209.8 187.9
Total inventory 1,375.0 $ 1,351.5
Lecanemab    
Inventory [Line Items]    
Work in process $ 118.0