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Financial Instruments (Tables)
 9 Months Ended
Sep. 30, 2022
Investments, Debt and Equity Securities [Abstract]  
Summary of financial assets with maturities of less than 90 days included within cash and cash equivalents
The following table summarizes our financial assets with maturities of less than 90 days from the date of purchase included in cash and cash equivalents in our condensed consolidated balance sheets:
(In millions)As of September 30, 2022As of December 31, 2021
Commercial paper$3.2 $247.6 
Overnight reverse repurchase agreements115.5 200.0 
Money market funds3,070.6 901.6 
Short-term debt securities2.5 283.0 
Total$3,191.8 $1,632.2 
Marketable debt and equity securities The following tables summarize our marketable debt and equity securities, classified as available-for-sale:
As of September 30, 2022
(In millions)Amortized
Cost		Gross
Unrealized
Gains		Gross
Unrealized
Losses		Fair
Value
Marketable debt securities
Corporate debt securities:
Current$833.6 $— $(6.9)$826.7 
Non-current400.5 — (8.1)392.4 
Government securities:
Current412.1 0.1 (3.5)408.7 
Non-current298.8 — (5.5)293.3 
Mortgage and other asset backed securities:
Current0.1 — — 0.1 
Non-current177.6 — (3.0)174.6 
Total marketable debt securities$2,122.7 $0.1 $(27.0)$2,095.8 
Marketable equity securities
Marketable equity securities, non-current$1,133.8 $— $(237.8)$896.0 
Total marketable equity securities$1,133.8 $— $(237.8)$896.0 
As of December 31, 2021
(In millions)Amortized
Cost		Gross
Unrealized
Gains		Gross
Unrealized
Losses		Fair
Value
Marketable debt securities
Corporate debt securities:
Current$723.6 $0.1 $(0.3)$723.4 
Non-current385.4 0.2 (0.8)384.8 
Government securities:
Current817.0 — (0.4)816.6 
Non-current377.0 0.1 (1.0)376.1 
Mortgage and other asset backed securities:
Current1.1 — — 1.1 
Non-current131.8 — (0.7)131.1 
Total marketable debt securities$2,435.9 $0.4 $(3.2)$2,433.1 
Marketable equity securities
Marketable equity securities, current$33.9 $9.9 $— $43.8 
Marketable equity securities, non-current1,133.1 151.0 (279.4)1,004.7 
Total marketable equity securities$1,167.0 $160.9 $(279.4)$1,048.5 
Summary of contractual maturities: available-for-sale securities
The estimated fair value and amortized cost of our marketable debt securities classified as available-for-sale by contractual maturity are summarized as follows:
 As of September 30, 2022As of December 31, 2021
(In millions)Estimated
Fair Value		Amortized
Cost		Estimated
Fair Value		Amortized
Cost
Due in one year or less$1,235.5 $1,245.8 $1,541.1 $1,541.7 
Due after one year through five years848.3 864.0 868.2 870.2 
Due after five years12.0 12.9 23.8 24.0 
Total marketable debt securities$2,095.8 $2,122.7 $2,433.1 $2,435.9 
Proceeds from marketable debt securities
The proceeds from maturities and sales of marketable debt securities and resulting realized gains and losses are summarized as follows:
 For the Three Months Ended September 30,For the Nine Months Ended September 30,
(In millions)2022202120222021
Proceeds from maturities and sales$1,643.2 $575.4 $3,104.7 $2,028.1 
Realized gains— 0.1 — 0.4 
Realized losses7.9 0.5 9.3 1.7