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Collaborative and Other Relationships - Equity Method Investments (Details)
₩ in Millions, $ in Millions
1 Months Ended 3 Months Ended 6 Months Ended
Apr. 30, 2022
USD ($)
Dec. 31, 2019
Jun. 30, 2022
USD ($)
Dec. 31, 2021
USD ($)
Sep. 30, 2021
USD ($)
Jun. 30, 2021
USD ($)
Mar. 31, 2020
USD ($)
Jun. 30, 2022
USD ($)
Jun. 30, 2021
USD ($)
Jun. 30, 2022
KRW (₩)
Mar. 31, 2022
KRW (₩)
Jan. 31, 2022
USD ($)
Dec. 31, 2021
KRW (₩)
Jan. 31, 2020
USD ($)
Nov. 07, 2018
USD ($)
Schedule of Equity Method Investments [Line Items]                              
Income (loss) from equity method investments               $ 2.6 $ 16.1            
Collaboration profit (loss) sharing     $ 29.4     $ (15.2)   (87.9) 53.3            
ADUHELM                              
Schedule of Equity Method Investments [Line Items]                              
Research and development expense               $ 275.0              
Samsung Bioepis                              
Schedule of Equity Method Investments [Line Items]                              
Percentage of stake in entity maximum     49.90%         49.90%   49.90%          
Amortization of basis differences                             $ 675.0
Loss recorded on Samsung Bioepis joint venture     $ 5.9     34.3   $ 2.6 16.1            
Income (loss) from equity method investments     13.0     41.6   17.0 30.6            
Investment in Samsung Bioepis       $ 599.9           ₩ 0.0     ₩ 713,300.0    
Collaboration profit (loss) sharing     58.3     69.9   122.7 138.4            
Eisai                              
Schedule of Equity Method Investments [Line Items]                              
Income (loss) from equity method investments     28.9     40.1   210.6 $ 40.1            
Due to Related Parties     56.0 46.5       $ 56.0              
Eisai | ADUHELM                              
Schedule of Equity Method Investments [Line Items]                              
Income (loss) from equity method investments     160.0 59.0 $ 45.0 $ 45.0                  
Samsung Bioepis                              
Schedule of Equity Method Investments [Line Items]                              
Proceeds from divestiture of interest in joint venture $ 1,000.0                            
Investment in Samsung Bioepis | ₩                     ₩ 581.6        
Payables to divestiture of interest in joint venture                       $ 1,300.0      
Equity Method Investments, Expected Profit Share   45.00%           50.00%              
Upfront and milestone payments made to collaborative partner             $ 100.0                
Research and development expense             $ 63.0                
Prepaid research and development expenses                           $ 37.0  
Accrued milestone payments     15.0                        
Estimated additional payments upon achievement of development and commercial milestones               $ 180.0              
Contract Option Exercise Fee               60.0              
Due to Related Parties     $ 121.1 $ 148.7       $ 121.1              
Samsung Bioepis | Payment Due At First Anniversary                              
Schedule of Equity Method Investments [Line Items]                              
Payables to divestiture of interest in joint venture                       812.5      
Samsung Bioepis | Payment Due At Second Anniversary                              
Schedule of Equity Method Investments [Line Items]                              
Payables to divestiture of interest in joint venture                       $ 437.5      
Inventory | Samsung Bioepis                              
Schedule of Equity Method Investments [Line Items]                              
Equity method investment basis difference amortization period               1 year 6 months              
Developed technology | Samsung Bioepis                              
Schedule of Equity Method Investments [Line Items]                              
Equity method investment basis difference amortization period               15 years