Other Consolidated Financial Statement (Details Textual) - USD ($) $ in Millions	3 Months Ended	6 Months Ended
Jun. 30, 2022	Jun. 30, 2021	Jun. 30, 2022	Jun. 30, 2021	Dec. 31, 2021
Net gains recognized on the increase in fair value of equity securities	$ (76.5)	$ 153.9	$ (267.4)	$ (288.4)
Net gains (losses) realized during the period on equity securities	(0.7)	$ 0.4	(0.5)	$ 6.6
Other long-term liabilities	1,167.8		1,167.8		$ 1,320.5
Accrued income taxes	499.6		$ 499.6		$ 664.5
Ionis, Sangamo, Denali and Sage
Net gains recognized on the increase in fair value of equity securities	$ 75.3

Carrying amount as of the balance sheet date of the unpaid sum of the known and estimated amounts payable to satisfy all domestic and foreign income tax obligations due beyond one year or the operating cycle, whichever is longer. Alternate captions include income taxes payable, noncurrent.

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